Understand the mechanisms being studied, the evidence available, and the questions that remain open.
Growth signalingCJC-1295 is a synthetic growth hormone-releasing hormone analog studied for prolonged stimulation of the growth hormone and IGF-1 axis. Online listings frequently blur the distinction between the albumin-binding DAC compound and other modified GHRH fragments. Those names should not be treated as interchangeable.
Growth signalingFollistatin is a regulatory protein that binds signaling molecules such as activins. It is not a simple short peptide, and it has multiple isoforms and biological roles. Online muscle-building discussions often reduce this complex biology to blocking myostatin, which can be misleading.
Growth signalingGHRP-2 is a synthetic growth hormone secretagogue used in endocrine research. It is also called pralmorelin. Changes in GH release and appetite are part of its pharmacology, but they do not establish an approved muscle-building or anti-aging treatment in the United States.
Growth signalingGHRP-6 is a synthetic growth hormone-releasing peptide studied as a secretagogue. It belongs to the ghrelin-receptor family of experimental compounds. Its name is often used in performance-oriented discussions, but hormone stimulation should not be presented as established evidence of better athletic recovery.
Growth signalingGonadorelin is a synthetic form of gonadotropin-releasing hormone. The endogenous hormone links hypothalamic signaling with pituitary release of reproductive hormones. Its diagnostic and therapeutic history should be separated from current wellness claims and from the status of a particular marketed formulation.
Growth signalingHexarelin is an experimental growth hormone-releasing peptide, also known as examorelin. It has been used to investigate endocrine responses and is sometimes promoted for muscle or recovery goals. A strong hormone response does not establish an approved or beneficial performance-enhancing treatment.
Growth signalingIGF-1 LR3 is a modified insulin-like growth factor used in research. It differs from native IGF-1 and from approved medicines containing other IGF-related formulations. A shared family name should not be used to transfer approval, dosing instructions, or clinical evidence between them.
Growth signalingIpamorelin is a synthetic pentapeptide and ghrelin-receptor agonist studied as a growth hormone secretagogue. It is often advertised alongside GHRH analogs, but an appealing combination rationale is not the same as clinical proof for recovery, muscle growth, or healthy aging.
Growth signalingKisspeptin refers to peptides involved in reproductive hormone signaling. Different forms, including kisspeptin-10 and kisspeptin-54, appear in research. The form, route, and patient population matter, so a generic kisspeptin label is not enough to identify the intervention.
Growth signalingMechano growth factor, or MGF, is a name connected to an IGF-1 splice variant and to research peptides derived from that biology. Online products labeled MGF or PEG-MGF may not represent the same molecular entity studied in gene-expression research.
Growth signalingSermorelin is the biologically active 29-amino-acid fragment of growth hormone-releasing hormone. It has a history in diagnostic and pediatric endocrine medicine. Its appearance in modern wellness marketing should not be mistaken for proof of an approved anti-aging or adult body-composition treatment.
Growth signalingTesamorelin is a growth hormone-releasing factor analog used in FDA-approved prescription products for excess abdominal fat in adults with HIV-associated lipodystrophy. That narrow indication is often lost in online descriptions that portray it as a general fat-loss or bodybuilding peptide.
| Compound | Research topic | Overview | Guide |
|---|---|---|---|
| CJC-1295 | Growth signaling | CJC-1295 is a synthetic growth hormone-releasing hormone analog studied for prolonged stimulation of the growth hormone and IGF-1 axis. Online listings frequently blur the distinction between the albumin-binding DAC compound and other modified GHRH fragments. Those names should not be treated as interchangeable. | Read ↗ |
| Follistatin | Growth signaling | Follistatin is a regulatory protein that binds signaling molecules such as activins. It is not a simple short peptide, and it has multiple isoforms and biological roles. Online muscle-building discussions often reduce this complex biology to blocking myostatin, which can be misleading. | Read ↗ |
| GHRP-2 | Growth signaling | GHRP-2 is a synthetic growth hormone secretagogue used in endocrine research. It is also called pralmorelin. Changes in GH release and appetite are part of its pharmacology, but they do not establish an approved muscle-building or anti-aging treatment in the United States. | Read ↗ |
| GHRP-6 | Growth signaling | GHRP-6 is a synthetic growth hormone-releasing peptide studied as a secretagogue. It belongs to the ghrelin-receptor family of experimental compounds. Its name is often used in performance-oriented discussions, but hormone stimulation should not be presented as established evidence of better athletic recovery. | Read ↗ |
| Gonadorelin | Growth signaling | Gonadorelin is a synthetic form of gonadotropin-releasing hormone. The endogenous hormone links hypothalamic signaling with pituitary release of reproductive hormones. Its diagnostic and therapeutic history should be separated from current wellness claims and from the status of a particular marketed formulation. | Read ↗ |
| Hexarelin | Growth signaling | Hexarelin is an experimental growth hormone-releasing peptide, also known as examorelin. It has been used to investigate endocrine responses and is sometimes promoted for muscle or recovery goals. A strong hormone response does not establish an approved or beneficial performance-enhancing treatment. | Read ↗ |
| IGF-1 LR3 | Growth signaling | IGF-1 LR3 is a modified insulin-like growth factor used in research. It differs from native IGF-1 and from approved medicines containing other IGF-related formulations. A shared family name should not be used to transfer approval, dosing instructions, or clinical evidence between them. | Read ↗ |
| Ipamorelin | Growth signaling | Ipamorelin is a synthetic pentapeptide and ghrelin-receptor agonist studied as a growth hormone secretagogue. It is often advertised alongside GHRH analogs, but an appealing combination rationale is not the same as clinical proof for recovery, muscle growth, or healthy aging. | Read ↗ |
| Kisspeptin | Growth signaling | Kisspeptin refers to peptides involved in reproductive hormone signaling. Different forms, including kisspeptin-10 and kisspeptin-54, appear in research. The form, route, and patient population matter, so a generic kisspeptin label is not enough to identify the intervention. | Read ↗ |
| MGF | Growth signaling | Mechano growth factor, or MGF, is a name connected to an IGF-1 splice variant and to research peptides derived from that biology. Online products labeled MGF or PEG-MGF may not represent the same molecular entity studied in gene-expression research. | Read ↗ |
| Sermorelin | Growth signaling | Sermorelin is the biologically active 29-amino-acid fragment of growth hormone-releasing hormone. It has a history in diagnostic and pediatric endocrine medicine. Its appearance in modern wellness marketing should not be mistaken for proof of an approved anti-aging or adult body-composition treatment. | Read ↗ |
| Tesamorelin | Growth signaling | Tesamorelin is a growth hormone-releasing factor analog used in FDA-approved prescription products for excess abdominal fat in adults with HIV-associated lipodystrophy. That narrow indication is often lost in online descriptions that portray it as a general fat-loss or bodybuilding peptide. | Read ↗ |